LDLR 抗体 (AA 705-860)
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北京 101111
Quick Overview for LDLR 抗体 (AA 705-860) (ABIN7876593)
抗原
See all LDLR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 705-860
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原理
- LDLR Antibody / LDL Receptor
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids A705-A860) was used as the immunogen for the LDLR antibody.
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亚型
- IgG
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anti-Low Density Lipoprotein Receptor (LDLR) (C-Term) antibody
KO Validated LDLR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor (LDLR) (AA 22-150) antibodyLDLR 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1B10H10 unconjugated
anti-Low Density Lipoprotein Receptor (LDLR) (AA 781-860) antibodyLDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, ELISA, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor (LDLR) antibodyLDLR 适用: 人 IHC, ELISA, FACS, IF 宿主: 兔 Monoclonal 2B10 unconjugated Recombinant Antibody
anti-Low Density Lipoprotein Receptor (LDLR) (AA 497-742) antibodyLDLR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor (LDLR) (AA 263-509) antibodyLDLR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor (LDLR) (AA 105-205) antibodyLDLR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E7 unconjugated
anti-Low Density Lipoprotein Receptor (LDLR) (AA 335-588) antibodyLDLR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor (LDLR) (AA 499-511) antibodyLDLR 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor (LDLR) (AA 391-419) antibodyLDLR 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB22886 unconjugated
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应用备注
- Optimal dilution of the LDLR antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the LDLR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LDLR (Low Density Lipoprotein Receptor (LDLR))
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别名
- LDLR
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背景
- In humans, the LDL receptor protein is encoded by the LDLR gene on chromosome 19. It is mapped to 19p13.2. The low absorbance lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low absorbance lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.
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UniProt
- P01130
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途径
- Hepatitis C, Lipid Metabolism
抗原
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