Neuropilin 1 抗体 (AA 700-900)
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Quick Overview for Neuropilin 1 抗体 (AA 700-900) (ABIN7876552)
抗原
See all Neuropilin 1 (NRP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 700-900
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原理
- Neuropilin-1 Antibody
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein (within amino acids 700-900) from the human protein was used as the immunogen for the Neuropilin-1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the Neuropilin-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Neuropilin-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Neuropilin 1 (NRP1)
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别名
- Neuropilin-1
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背景
- Neuropilin is a type I transmembrane receptor that has been implicated in aspects of axon growth and guidance and has been shown to act as a high affinity receptor for class III semaphorins and vascular endothelial growth factor (VEGF). A closely related protein, neuropilin-2, shares a common domain structure and signifcant homology with neuropilin and also acts as a receptor for the class III semaphorins and VEGF. Both neuropilins are involved in regulating many physiological pathways including axonal guidance and angiogenesis, however they exhibit differential expression in the adult vasculature. Neuropilin-2 is polysialylated and expressed on the surface of dendritic cells. It is also expressed by venous and lymphatic endothelium. Neuropilin is expressed predominantly by arterial endothelium.
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UniProt
- O14786
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途径
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
抗原
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