DR1 抗体 (AA 7-154)
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Quick Overview for DR1 抗体 (AA 7-154) (ABIN7876466)
抗原
See all DR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 7-154
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原理
- DR1 Antibody / Down-regulator of transcription 1
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids N7-A154) was used as the immunogen for the DR1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the DR1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the DR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
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别名
- DR1
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背景
- Protein Dr1 is a protein that in humans is encoded by the DR1 gene. This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
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UniProt
- Q01658
抗原
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