Adrenomedullin 抗体 (AA 69-96)
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Quick Overview for Adrenomedullin 抗体 (AA 69-96) (ABIN7876453)
抗原
See all Adrenomedullin (ADM) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 69-96
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原理
- Adrenomedullin antibody / ADM
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 69-96 from the human protein was used as the immunogen for the Adrenomedullin antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Adrenomedullin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Adrenomedullin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Adrenomedullin (ADM)
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别名
- Adrenomedullin
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物质类
- Hormone
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背景
- ADM, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes.
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UniProt
- P35318
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途径
- Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
抗原
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