Thyroperoxidase 抗体 (AA 685-804)
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Quick Overview for Thyroperoxidase 抗体 (AA 685-804) (ABIN7876416)
抗原
See all Thyroperoxidase (TPO) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 685-804
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原理
- Thyroid Peroxidase Antibody / TPO (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 685-804 from the human protein was used as the immunogen for the Thyroid Peroxidase antibody.
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亚型
- IgG1, kappa
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anti-Thyroid Peroxidase (TPO) (AA 672-779) antibody
TPO 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Thyroid Peroxidase (TPO) (AA 1-933) antibodyTPO 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 111-210) antibodyTPO 适用: 人, 大鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (C-Term) antibodyVerified TPO 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 636-832) antibodyTPO 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 107-276) antibodyTPO 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 19-846) antibodyTPO 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 1-933) antibodyTPO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (C-Term) antibody (Biotin)Verified TPO 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal Biotin
anti-Thyroid Peroxidase (TPO) (Internal Region) antibody (Biotin)Verified TPO 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal Biotin
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应用备注
- Optimal dilution of the Thyroid Peroxidase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Thyroid Peroxidase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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别名
- Thyroid Peroxidase
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背景
- Thyroperoxidase (TPO) is a 933 amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors.
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UniProt
- P07202
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途径
- Thyroid Hormone Synthesis
抗原
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