CDK14 抗体 (AA 67-96)
Our Local Distributor
北京 101111
Quick Overview for CDK14 抗体 (AA 67-96) (ABIN7876387)
抗原
See all CDK14 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 67-96
-
原理
- CDK14 Antibody / Cyclin-dependent kinase 14 / PFTAIRE-1
-
纯化方法
- SAS precipitation
-
免疫原
- A portion of amino acids 67-96 from the human protein was used as the immunogen for the CDK14 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the CDK14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the CDK14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- CDK14 (Cyclin-Dependent Kinase 14 (CDK14))
-
别名
- CDK14
-
背景
- Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport. [UniProt]
-
UniProt
- O94921
抗原
-