PFKL 抗体 (AA 669-699)
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北京 101111
Quick Overview for PFKL 抗体 (AA 669-699) (ABIN7876365)
抗原
See all PFKL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 669-699
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原理
- PFKL Antibody / ATP-PFK / ATP-dependent 6-phosphofructokinase liver type
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免疫原
- A portion of amino acids 669-699 from the human protein was used as the immunogen for the PFKL antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the PFKL antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PFKL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PFKL (Phosphofructokinase, Liver (PFKL))
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别名
- PFKL
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背景
- The PFKL protein is an enzyme that catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, a key step in the glycolytic pathway. It also plays a role in regulating glucose metabolism, which is crucial for maintaining healthy blood sugar levels. Dysregulation of the PFKL protein has been linked to metabolic disorders such as diabetes and obesity. While it is primarily found in the liver, where it helps regulate glucose production, it is also found in other tissues such as skeletal muscle and adipose tissue.
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UniProt
- P17858
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途径
- Negative Regulation of Hormone Secretion, Warburg Effect
抗原
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