SEZ6L 抗体 (AA 662-953)
This 兔 多克隆 antibody specifically detects SEZ6L in WB, ELISA, FACS 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7876361
发货至:
中国
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Quick Overview for SEZ6L 抗体 (AA 662-953) (ABIN7876361)
抗原
See all SEZ6L 抗体
SEZ6L
(Seizure Related 6 Homolog Like (SEZ6L))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This SEZ6L antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
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抗原表位
- AA 662-953
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原理
- SEZ6L Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids E662-E953) was used as the immunogen for the SEZ6L antibody.
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亚型
- IgG
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anti-Seizure Related 6 Homolog Like (SEZ6L) (AA 662-953) antibody
SEZ6L 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Seizure Related 6 Homolog Like (SEZ6L) (AA 701-800) antibodySEZ6L 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SEZ6L antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SEZ6L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SEZ6L (Seizure Related 6 Homolog Like (SEZ6L))
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别名
- SEZ6L
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背景
- Seizure 6-like protein is a protein that in humans is encoded by the SEZ6L gene. SEZ6L (Seizure 6-Like protein, also BSRP-B in rodent) is a 200 kDa member of the SEZ6 family of proteins. It is expressed in the plasma membrane and ER of CNS neurons and lung bronchiolar epithelium, and likely regulates PKC alpha activation. Mature human SEZ6L is a 996 amino acid (aa) type I transmembrane protein. It contains a 930 aa extracellular domain (ECD) (aa 29-958) plus a 45 aa cytoplasmic tail. The ECD shows three CUB domains and five short consensus repeats (SCRs). There are multiple isoforms possible for SEZ6L. One shows a deletion of aa 933-943, and a second shows the same deletion coupled to a Thr substitution for aa 803-867. A third isoform contains a Leu substitution for aa 867-943. An alternative start site is reported at Met228. This start site may occur individually, or be accompanied by a deletion of aa 932-944, the same deletion of aa 932-944 coupled to a Thr substitution for aa 803-867, or a duel deletion of aa 869-945 and 1016-1024. Over aa 29-958, human BSRP-B is 80 % aa identical to mouse BSRP-B.
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UniProt
- Q9BYH1
抗原
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