Recombinant CD86 抗体 (AA 66-195)
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Quick Overview for Recombinant CD86 抗体 (AA 66-195) (ABIN7876324)
抗原
See all CD86 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 66-195
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原理
- Recombinant CD86 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 66-195 was used as the immunogen for the recombinant CD86 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the recombinant CD86 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant CD86 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD86
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别名
- CD86
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背景
- Recognizes a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkins disease.
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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