SH3G2 抗体 (AA 65-292)
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Quick Overview for SH3G2 抗体 (AA 65-292) (ABIN7876278)
抗原
See all SH3G2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 65-292
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原理
- Endophilin A1 Antibody / SH3GL2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids R65-Q292) was used as the immunogen for the Endophilin A1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Endophilin A1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Endophilin A1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SH3G2 (Endophilin-A1 (SH3G2))
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别名
- Endophilin A1
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背景
- Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene. Endophilin proteins are part of a large family of Bin/Amphiphysin/Rvs (BAR) domain proteins that are involved in cell membrane remodeling. The endophilins are encoded by five genes, which produce endophilin A 1-3 and B 1-2. Endophilins are involved in many cellular mechanisms, such as synaptic vesicle recycling, receptor trafficking, and membrane remodeling processes. Research studies indicate that endophilin 1 (endophilin A1, SH3GL2) can induce different membrane shapes and participate in the morphogenesis of dendritic spines. Endophilin 1 is also involved in regulating blood brain barrier permeability via the EGFR-JNK pathway.
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UniProt
- Q99962
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途径
- Neurotrophin Signaling Pathway, EGFR Downregulation
抗原
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