UBE2I 抗体 (AA 65-146)
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Quick Overview for UBE2I 抗体 (AA 65-146) (ABIN7876272)
抗原
See all UBE2I 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 65-146
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原理
- UBC9 Antibody / UBE2I
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids K65-K146 ) was used as the immunogen for the UBC9 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the UBC9 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the UBC9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))
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别名
- UBC9
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背景
- SUMO-conjugating enzyme UBC9 (UBE2I), also called UBC9, is a protein that in humans is encoded by the UBE2I gene. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. It is mapped to 16p13.3. UBC9 could fully complement the mutant phenotype of a yeast ubc9 mutant strain. This gene may play a similar role via interaction with WT1, which is able to impose a block to cell cycle progression in eukaryotic cells. What's more, it could support the growth of yeast ubc9 temperature-sensitive mutants at nonpermissive temperatures, indicating that the gene is a functional homolog of yeast ubc9. UBC9 is specifically associated with FHIT, such as FHIT may be involved in cell cycle control through its interaction with UBC9.
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UniProt
- P63279
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway
抗原
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