LARS 抗体 (AA 628-855)
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Quick Overview for LARS 抗体 (AA 628-855) (ABIN7876202)
抗原
See all LARS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 628-855
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原理
- Leucyl tRNA synthetase Antibody / LARS
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids Q628-Q855 from the human protein were used as the immunogen for the Leucyl tRNA synthetase antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Leucyl tRNA synthetase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Leucyl tRNA synthetase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LARS (Leucyl-tRNA Synthetase (LARS))
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别名
- Leucyl tRNA synthetase
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背景
- Leucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the LARS gene. This gene is mapped to 5q32. It encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed.
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UniProt
- Q9P2J5
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途径
- EGFR Signaling Pathway
抗原
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