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Dynamin 1-Like 抗体 (AA 618-736)

The 兔 多克隆 anti-Dynamin 1-Like antibody is suitable to detect Dynamin 1-Like in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF, FACS 和 IHC (p).
产品编号 ABIN7876143
发货至: 中国
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Quick Overview for Dynamin 1-Like 抗体 (AA 618-736) (ABIN7876143)

抗原

See all Dynamin 1-Like (DNM1L) 抗体
Dynamin 1-Like (DNM1L)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Dynamin 1-Like antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 618-736

    原理

    DNM1L Antibody / DRP1

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids Q618-W736) was used as the immunogen for the DNM1L antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the DNM1L antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the DNM1L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Dynamin 1-Like (DNM1L)

    别名

    DNM1L

    背景

    Dynamin-1-like protein is a GTPase that regulates mitochondrial fission. In humans, dynamin-1-like protein, which is typically referred to as dynamin-related protein 1 (Drp1), is encoded by the DNM1L gene. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

    UniProt

    O00429
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