PCDHAC2 抗体 (AA 616-644)
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Quick Overview for PCDHAC2 抗体 (AA 616-644) (ABIN7876139)
抗原
See all PCDHAC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 616-644
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原理
- Protocadherin alpha-C2 Antibody / PCDHAC2
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 616-644 from the human protein was used as the immunogen for the Protocadherin alpha-C2 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Protocadherin alpha-C2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Protocadherin alpha-C2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))
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别名
- Protocadherin alpha-C2
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背景
- This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
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UniProt
- Q9Y5I4
抗原
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