AXIN2 抗体 (AA 614-843)
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Quick Overview for AXIN2 抗体 (AA 614-843) (ABIN7876137)
抗原
See all AXIN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 614-843
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原理
- AXIN2 Antibody / Axis inhibition protein 2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human Axin 2/AXIN2 protein (amino acids D614-D843) was used as the immunogen for the AXIN2 antibody.
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亚型
- IgG
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anti-Axin 2 (AXIN2) (AA 614-843) antibody
AXIN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 816-843) antibodyAXIN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 56-73) antibodyAXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 816-843), (C-Term) antibodyAXIN2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26798 unconjugated
anti-Axin 2 (AXIN2) (AA 331-430) antibodyAXIN2 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 350-631) antibodyAXIN2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 611-710) antibodyAXIN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Axin 2 (AXIN2) (N-Term) antibodyAXIN2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 11-77) antibodyAXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) antibodyAXIN2 适用: 人 WB 宿主: 兔 Monoclonal 23GB1545 unconjugated Recombinant Antibody
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应用备注
- Optimal dilution of the AXIN2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the AXIN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- AXIN2 (Axin 2 (AXIN2))
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别名
- AXIN2
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背景
- Axin-2 also known as axin-like protein (Axil) or axis inhibition protein 2 (AXIN2) or conductin is a protein that in humans is encoded by the AXIN2 gene. The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
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UniProt
- Q9Y2T1
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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