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Recombinant L1CAM 抗体 (AA 600-900)

The 兔 单克隆 anti-L1CAM antibody is suitable to detect L1CAM in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7876059
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant L1CAM 抗体 (AA 600-900) (ABIN7876059)

抗原

See all L1CAM 抗体
L1CAM (L1 Cell Adhesion Molecule (L1CAM))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This L1CAM antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

L1CAM-9267R
  • 抗原表位

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    AA 600-900

    原理

    Recombinant CD171 Antibody / NCAM-L1 / L1CAM

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment (within amino acids 600-900) of human L1CAM protein was used as the immunogen for the recombinant CD171 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant CD171 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant CD171 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    L1CAM (L1 Cell Adhesion Molecule (L1CAM))

    别名

    CD171

    背景

    L1 (L1 cell adhesion molecule) also known as CAML1, CD171, and HSAS is an adhesion molecule which plays an important role in the nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). This mouse monoclonal antibody recognizes the sequence immediately NH2-terminal to the tyrosine-based motif and binds L1 only when Y1176 is dephosphorylated. Phosphorylation of either T1172 or Y1176 strongly inhibits binding of 74-5H7 to the L1 cytoplasmic domain.

    UniProt

    P32004

    途径

    Synaptic Membrane
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