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FBXO32 抗体 (AA 6-355)

The 兔 多克隆 anti-FBXO32 antibody is suitable to detect FBXO32 in samples from 人 和 小鼠. It has been validated for WB, ELISA, IF 和 FACS.
产品编号 ABIN7875957
发货至: 中国
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Quick Overview for FBXO32 抗体 (AA 6-355) (ABIN7875957)

抗原

See all FBXO32 抗体
FBXO32 (F-Box Protein 32 (FBXO32))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This FBXO32 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 6-355

    原理

    FBXO32 Antibody / F-box only protein 32 / Atrogin 1

    纯化方法

    Antigen affinity purified

    免疫原

    An E.coli-derived human recombinant protein (amino acids Q6-F355) was used as the immunogen for the FBXO32 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the FBXO32 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the FBXO32 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    FBXO32 (F-Box Protein 32 (FBXO32))

    别名

    FBXO32

    背景

    F-box only protein 32, also known as MAFbx, for Muscle Atrophy F-box gene, and Atrogin-1, is a protein that in humans is encoded by the FBXO32 gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

    UniProt

    Q969P5
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