GPC1 抗体 (AA 6-31)
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北京 101111
Quick Overview for GPC1 抗体 (AA 6-31) (ABIN7875951)
抗原
See all GPC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-31
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原理
- Glypican-1 Antibody / GPC1
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免疫原
- A portion of amino acids 6-31 from the human protein was used as the immunogen for the Glypican-1 antibody.
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亚型
- Ig Fraction
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anti-Glypican 1 (GPC1) antibody
KO Validated GPC1 适用: 人 WB, ELISA, ICC, IP, IF, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 155-292) antibodyGPC1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 342-530) antibodyGPC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 24-131) antibodyGPC1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glypican 1 (GPC1) antibodyGPC1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB13580 unconjugated Recombinant Antibody
anti-Glypican 1 (GPC1) (AA 12-41), (N-Term) antibodyGPC1 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 301-400) antibodyGPC1 适用: 人 ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 114-277) antibodyGPC1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 343-545) antibodyGPC1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (Internal Region) antibodyVerified GPC1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Glypican-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Glypican-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GPC1 (Glypican 1 (GPC1))
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别名
- Glypican-1
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背景
- Glypican-1, also known as GPC1, is a glycosylphosphatidylinositol (GPI)-anchored cell surface proteoglycan that plays a crucial role in various cellular processes, including cell growth, differentiation, and signaling pathways. Recent studies have shown that GPC1 is overexpressed in many types of cancer, including pancreatic, breast, and prostate cancer. This overexpression is thought to contribute to the aggressiveness and metastatic potential of these tumors, making GPC1 a potential target for cancer therapy. One of the key functions of GPC1 in cancer is its ability to interact with growth factors and signaling molecules, such as Wnt and Hedgehog, to promote tumor growth and progression. By blocking the interaction between GPC1 and these molecules, researchers believe they can inhibit the growth of cancer cells and potentially prevent metastasis. In addition to its role in promoting cancer progression, GPC1 has also been found to be a promising biomarker for early detection and prognosis of cancer. Researchers have developed novel diagnostic tools that detect circulating GPC1 levels in the blood, allowing for earlier detection of cancer and more accurate monitoring of treatment response.
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UniProt
- P35052
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途径
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
抗原
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