OCIAD2 抗体 (AA 6-138)
Our Local Distributor
北京 101111
Quick Overview for OCIAD2 抗体 (AA 6-138) (ABIN7875939)
抗原
See all OCIAD2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 6-138
-
原理
- OCIAD2 Antibody / OCIA domain containing 2
-
纯化方法
- Immunogen affinity purified
-
免疫原
- E.coli-derived human OCIAD2 recombinant protein (Position: A6-K138) was used as the immunogen for the OCIAD2 antibody.
-
亚型
- IgG
-
-
anti-OCIA Domain Containing 2 (OCIAD2) (C-Term) antibody
OCIAD2 适用: 人 WB, IF, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-OCIA Domain Containing 2 (OCIAD2) (AA 1-99) antibodyOCIAD2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-OCIA Domain Containing 2 (OCIAD2) (N-Term) antibodyOCIAD2 适用: 人, 小鼠, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-OCIA Domain Containing 2 (OCIAD2) (AA 72-121) antibodyOCIAD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-OCIA Domain Containing 2 (OCIAD2) (AA 1-154) antibodyOCIAD2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-OCIA Domain Containing 2 (OCIAD2) (N-Term) antibodyOCIAD2 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the OCIAD2 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the OCIAD2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- OCIAD2 (OCIA Domain Containing 2 (OCIAD2))
-
别名
- OCIAD2
-
背景
-
OCIAD2 antibody detects OCIA domain-containing protein 2, encoded by the OCIAD2 gene on chromosome 4q31.21. OCIAD2 antibody is widely used in cancer biology, mitochondrial research, and developmental studies. OCIAD2 is a mitochondrial inner membrane protein implicated in oxidative phosphorylation regulation and cell signaling. It has been studied for its roles in ovarian cancer and other malignancies, where it influences tumor progression and chemoresistance.
Structurally, OCIAD2 is a ~17 kDa protein with a conserved OCIA domain mediating protein-protein interactions. It localizes to mitochondria and interacts with components of the respiratory chain. OCIAD2 may also associate with signaling molecules, linking mitochondrial metabolism with cell signaling pathways. Multiple isoforms may provide tissue-specific functions.
Functionally, OCIAD2 regulates mitochondrial activity by modulating electron transport chain components, influencing ATP production and reactive oxygen species generation. It has also been implicated in cell adhesion, proliferation, and survival. Researchers use OCIAD2 antibody to study mitochondrial function, cancer biology, and signaling networks.
Clinically, OCIAD2 is overexpressed in ovarian, lung, and breast cancers, correlating with poor prognosis and chemoresistance. It is being investigated as a biomarker of malignancy and as a therapeutic target. NSJ Bioreagents provides OCIAD2 antibody for studies of mitochondrial biology, cancer progression, and therapeutic development.
Experimentally, OCIAD2 antibody is used in western blotting to detect the ~17 kDa protein, in immunofluorescence to study mitochondrial localization, and in immunohistochemistry to analyze tumor expression. Co-immunoprecipitation with OCIAD2 antibody helps identify mitochondrial and signaling partners. -
UniProt
- Q56VL3
抗原
-
