MCM8 抗体 (AA 598-840)
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Quick Overview for MCM8 抗体 (AA 598-840) (ABIN7875936)
抗原
See all MCM8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 598-840
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原理
- MCM8 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids N598-M840) was used as the immunogen for the MCM8 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MCM8 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MCM8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
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别名
- MCM8
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背景
- DNA replication licensing factor MCM8 is a protein that in humans is encoded by the MCM8 gene. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. And this protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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UniProt
- Q9UJA3
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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