ADRBK2 抗体 (AA 591-688)
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Quick Overview for ADRBK2 抗体 (AA 591-688) (ABIN7875917)
抗原
See all ADRBK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 591-688
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原理
- ADRBK2 Antibody / Beta-ARK-2 / GRK3
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids R591-L688) was used as the immunogen for the ADRBK2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ADRBK2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ADRBK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))
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别名
- ADRBK2
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背景
- Beta-adrenergic receptor kinase 2 (beta-ARK-2), also known as G-protein-coupled receptor kinase 3 (GRK3), is an enzyme that in humans is encoded by theADRBK2gene. The human ADRBK2 gene is located on 22q11. The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85 % amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95 % similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
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UniProt
- P35626
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
抗原
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