NUMB 抗体 (AA 59-567)
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Quick Overview for NUMB 抗体 (AA 59-567) (ABIN7875909)
抗原
See all NUMB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-567
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原理
- NUMB Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids E59-A567) was used as the immunogen for the NUMB antibody.
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亚型
- IgG
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anti-Numb Homolog (NUMB) (C-Term) antibody
Verified NUMB 适用: 人, 小鼠 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 521-640) antibodyNUMB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) antibodyKD Validated NUMB 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1070 unconjugated Recombinant Antibody
anti-Numb Homolog (NUMB) (AA 194-220), (N-Term) antibodyNUMB 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 1-135) antibodyNUMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A7-A6 unconjugated
anti-Numb Homolog (NUMB) (AA 1-50) antibodyNUMB 适用: 人, 小鼠, 大鼠, 猴, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) antibodyKD Validated NUMB 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB940 unconjugated Recombinant Antibody
anti-Numb Homolog (NUMB) (pSer276) antibodyNUMB 适用: 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 1-135) antibodyNUMB 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 1-214) antibodyNUMB 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the NUMB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NUMB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NUMB (Numb Homolog (NUMB))
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别名
- NUMB
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背景
- Protein numb homolog is a protein that in humans is encoded by the NUMB gene. It is mapped to 14q24.2 to q24.3. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. The primary function of Numb in cell differentiation is as an inhibitor of Notch signaling which is essential for maintaining self-renewal potential in stem and progenitor cells. Numb also plays a crucial role in asymmetrical cell division during development, allowing for differential cell fate specification in the central and peripheral nervous systems. Whati 1/2s more, the numb gene protein product controls binary cell fate decisions in the peripheral and central nervous systems of both invertebrates and mammals during neurogenesis.
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UniProt
- P49757
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途径
- Cell-Cell Junction Organization
抗原
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