GRAF 抗体 (AA 584-791)
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Quick Overview for GRAF 抗体 (AA 584-791) (ABIN7875870)
抗原
See all GRAF (ARHGAP26) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 584-791
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原理
- ARHGAP26 Antibody / GRAF
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids S584-E791) was used as the immunogen for the ARHGAP26 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ARHGAP26 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ARHGAP26 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
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别名
- ARHGAP26
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背景
- Rho GTPase activating protein 26 (ARHGAP26) also known as GTPase Regulator Associated with Focal Adhesion Kinase (GRAF) is a protein that in humans is encoded by the ARHGAP26 gene. Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q9UNA1
抗原
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