GAR1 抗体 (AA 58-165)
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Quick Overview for GAR1 抗体 (AA 58-165) (ABIN7875836)
抗原
See all GAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 58-165
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原理
- GAR1 Antibody / H/ACA ribonucleoprotein complex subunit 1 / NOLA1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids F58-K165) was used as the immunogen for the GAR1 antibody.
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亚型
- IgG
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anti-GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1) (AA 58-165) antibody
GAR1 适用: 人 ELISA, WB, IHC, IF, ICC, FACS, IP 宿主: 兔 Polyclonal unconjugated
anti-GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1) (AA 86-114) antibodyGAR1 适用: 人 WB 宿主: 兔 Polyclonal RB39831 unconjugated
anti-GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1) (Internal Region) antibodyGAR1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1) (AA 1-217) antibodyGAR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the GAR1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the GAR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GAR1 (GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1))
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别名
- GAR1
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背景
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GAR1 (H/ACA ribonucleoprotein complex subunit 1) is a highly conserved nucleolar protein that functions as an essential component of the H/ACA small nucleolar ribonucleoprotein (snoRNP) complex. This complex guides site-specific pseudouridylation of ribosomal RNA, a critical modification for ribosome biogenesis and proper protein synthesis.
GAR1 interacts with other snoRNP core proteins, including DKC1, NOP10, and NHP2, to ensure stability and catalytic activity of the H/ACA complex. Beyond its role in rRNA processing, GAR1 has been implicated in telomerase function and the regulation of RNA stability. Disruption of GAR1 activity has been associated with ribosomopathies and defects in cellular proliferation.
Using a high-quality GAR1 antibody enables accurate detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A GAR1 antibody from NSJ Bioreagents provides sensitivity and reproducibility for research in RNA modification, ribosome assembly, and nucleolar biology. Selecting the right GAR1 antibody is essential for generating reliable and consistent results.
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UniProt
- Q9NY12
抗原
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