MAGE-Like 2 抗体 (AA 578-847)
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Quick Overview for MAGE-Like 2 抗体 (AA 578-847) (ABIN7875833)
抗原
See all MAGE-Like 2 (MAGEL2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 578-847
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原理
- MAGEL2 Antibody / MAGE-like protein 2
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids Q578-A847) was used as the immunogen for the MAGEL2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MAGEL2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MAGEL2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MAGE-Like 2 (MAGEL2)
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别名
- MAGEL2
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背景
- Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
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UniProt
- Q9UJ55
抗原
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