GLDC 抗体 (AA 574-1020)
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Quick Overview for GLDC 抗体 (AA 574-1020) (ABIN7875823)
抗原
See all GLDC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 574-1020
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原理
- GLDC Antibody / Glycine Decarboxylase
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids K574-S1020) was used as the immunogen for the GLDC antibody.
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亚型
- IgG1
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应用备注
- Optimal dilution of the GLDC antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the GLDC antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GLDC (Glycine Dehydrogenase (GLDC))
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别名
- GLDC
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背景
- Glycine decarboxylase also known as glycine cleavage system P protein or glycine dehydrogenase is an enzyme that in humans is encoded by the GLDC gene. Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
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UniProt
- P23378
抗原
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