OSTF1 抗体 (AA 57-190)
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Quick Overview for OSTF1 抗体 (AA 57-190) (ABIN7875797)
抗原
See all OSTF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 57-190
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原理
- Zebrafish Ostf1 Antibody / Osteoclast-stimulating factor 1
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Ostf1 recombinant protein (amino acids R57-K190) was used as the immunogen for the Zebrafish Ostf1 antibody.
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亚型
- Ig Fraction
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anti-Osteoclast Stimulating Factor 1 (OSTF1) (AA 1-217) antibody
OSTF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Osteoclast Stimulating Factor 1 (OSTF1) (AA 1-217) antibodyOSTF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-Osteoclast Stimulating Factor 1 (OSTF1) (AA 1-217) antibodyOSTF1 适用: 人 WB, ELISA, ICC, IF, FACS 宿主: 小鼠 Monoclonal AT9G4 unconjugated
anti-Osteoclast Stimulating Factor 1 (OSTF1) (AA 43-92) antibodyOSTF1 适用: 人, 犬, 斑马鱼, 豚鼠, 马, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Osteoclast Stimulating Factor 1 (OSTF1) (AA 10-37), (N-Term) antibodyOSTF1 适用: 人 WB 宿主: 兔 Polyclonal RB37051 unconjugated
anti-Osteoclast Stimulating Factor 1 (OSTF1) (AA 10-215) antibodyOSTF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Osteoclast Stimulating Factor 1 (OSTF1) (AA 12-214) antibodyOSTF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Ostf1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Ostf1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- OSTF1 (Osteoclast Stimulating Factor 1 (OSTF1))
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别名
- Ostf1
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背景
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Ostf1, or osmotic stress transcription factor one, is a regulatory protein that plays an important role in the cellular response to osmotic stress and ion transport. It is involved in the regulation of genes that control osmoregulation, ion balance, and epithelial function, particularly in tissues exposed to changing environmental salinity.
In zebrafish, Ostf1 is strongly expressed in the gills, kidney, and other osmoregulatory organs, where it contributes to the adaptation of cells to changes in external ionic and osmotic conditions. Zebrafish Ostf1 is an ortholog of the human OSTF1 gene. Both zebrafish and human proteins share conserved structural features, including domains involved in transcriptional regulation and protein interactions.
Functionally, Ostf1 acts as an intracellular signaling mediator that is activated in response to hyperosmotic stress. In zebrafish, it has been shown to regulate the expression of ion transporters and channels, including those involved in sodium and chloride balance. It may also contribute to the remodeling of gill epithelium and the function of mitochondrion-rich cells during osmotic adaptation.
Ostf1 is also implicated in developmental processes and stress signaling pathways beyond osmoregulation. Because of its conservation and functional importance, zebrafish Ostf1 is widely used in studies of environmental stress physiology, aquaculture research, and basic cell signaling.
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UniProt
- Q6TGW5
抗原
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