ACTN2 抗体 (AA 567-696)
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Quick Overview for ACTN2 抗体 (AA 567-696) (ABIN7875795)
抗原
See all ACTN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 567-696
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原理
- ACTN2 Antibody / Alpha Actinin 2 / Sarcomeric Alpha Actinin
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived human protein (amino acids E567-E696) was used as the immunogen for the ACTN2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ACTN2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ACTN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ACTN2 (Actinin, alpha 2 (ACTN2))
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别名
- ACTN2
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背景
- Alpha-actinin 2 is a protein which in humans is encoded by the ACTN2 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P35609
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途径
- Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
抗原
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