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ACTN2 抗体 (AA 567-696)

The 兔 多克隆 anti-ACTN2 antibody is suitable to detect ACTN2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC (p) 和 FACS.
产品编号 ABIN7875795
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ACTN2 抗体 (AA 567-696) (ABIN7875795)

抗原

See all ACTN2 抗体
ACTN2 (Actinin, alpha 2 (ACTN2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ACTN2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

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    AA 567-696

    原理

    ACTN2 Antibody / Alpha Actinin 2 / Sarcomeric Alpha Actinin

    纯化方法

    Affinity purified

    免疫原

    An E. coli-derived human protein (amino acids E567-E696) was used as the immunogen for the ACTN2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the ACTN2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the ACTN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ACTN2 (Actinin, alpha 2 (ACTN2))

    别名

    ACTN2

    背景

    Alpha-actinin 2 is a protein which in humans is encoded by the ACTN2 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

    UniProt

    P35609

    途径

    Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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