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Emerin 抗体 (AA 56-167)

The 小鼠 单克隆 anti-Emerin antibody (Clone EMD-2167) (ABIN7875760) specifically detects Emerin in WB, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7875760
发货至: 中国
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Quick Overview for Emerin 抗体 (AA 56-167) (ABIN7875760)

抗原

See all Emerin (EMD) 抗体
Emerin (EMD)

适用

  • 93
  • 27
  • 24
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 62
  • 31
  • 2
小鼠

克隆类型

  • 51
  • 44
单克隆

标记

  • 45
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Emerin antibody is un-conjugated

应用范围

  • 82
  • 44
  • 37
  • 18
  • 18
  • 15
  • 13
  • 13
  • 11
  • 9
  • 6
  • 3
  • 2
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  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

EMD-2167
  • 抗原表位

    • 25
    • 15
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    AA 56-167

    原理

    Emerin Antibody

    纯化方法

    Protein G affinity chromatography

    免疫原

    A portion of amino acids 56-167 from the human protein was used as the immunogen for the Emerin antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Titering of the Emerin antibody may be required for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Emerin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Emerin (EMD)

    别名

    Emerin

    背景

    Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.

    UniProt

    P50402
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