ACTN2 抗体 (AA 557-692)
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Quick Overview for ACTN2 抗体 (AA 557-692) (ABIN7875737)
抗原
See all ACTN2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 557-692
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原理
- ACTN2 Antibody / Alpha Actinin 2 / Sarcomeric Alpha Actinin
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 557-692 from the human protein were used as the immunogen for this ACTN2 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the ACTN2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the ACTN2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- ACTN2 (Actinin, alpha 2 (ACTN2))
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别名
- ACTN2
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背景
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P35609
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途径
- Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
抗原
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