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ACTN2 抗体 (AA 557-692)

The 小鼠 单克隆 anti-ACTN2 antibody (Clone ACTN2-3291) (ABIN7875736) specifically detects ACTN2 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7875736
发货至: 中国
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Quick Overview for ACTN2 抗体 (AA 557-692) (ABIN7875736)

抗原

See all ACTN2 抗体
ACTN2 (Actinin, alpha 2 (ACTN2))

适用

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宿主

  • 103
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小鼠

克隆类型

  • 86
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单克隆

标记

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This ACTN2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

ACTN2-3291
  • 抗原表位

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    AA 557-692

    原理

    ACTN2 Antibody / Alpha Actinin 2 / Sarcomeric Alpha Actinin (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    Amino acids 557-692 from the human protein were used as the immunogen for this ACTN2 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the ACTN2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the ACTN2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    ACTN2 (Actinin, alpha 2 (ACTN2))

    别名

    ACTN2

    背景

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

    UniProt

    P35609

    途径

    Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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