SNRNP200 抗体 (AA 557-2129)
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Quick Overview for SNRNP200 抗体 (AA 557-2129) (ABIN7875725)
抗原
See all SNRNP200 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 557-2129
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原理
- SNRNP200 Antibody / U5 snRNP-specific 200 kDa protein
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids K557-A2129) was used as the immunogen for the SNRNP200 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SNRNP200 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SNRNP200 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))
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别名
- SNRNP200
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背景
- U5 small nuclear ribonucleoprotein 200 kDa helicase is an enzyme that in humans is encoded by the SNRNP200 gene. Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
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UniProt
- O75643
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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