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Exportin 2 抗体 (AA 55-84)

The 兔 多克隆 anti-Exportin 2 antibody (ABIN7875700) specifically detects Exportin 2 in WB, IF 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7875700
发货至: 中国
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Quick Overview for Exportin 2 抗体 (AA 55-84) (ABIN7875700)

抗原

See all Exportin 2 (CSE1L) 抗体
Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

适用

  • 46
  • 25
  • 10
  • 7
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 39
  • 7

克隆类型

  • 25
  • 21
多克隆

标记

  • 34
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Exportin 2 antibody is un-conjugated

应用范围

  • 42
  • 27
  • 24
  • 18
  • 10
  • 10
  • 10
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 55-84

    原理

    Exportin 2 Antibody / CSE1L

    纯化方法

    SAS precipitation

    免疫原

    A portion of amino acids 55-84 from the human protein was used as the immunogen for the Exportin 2 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the Exportin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Exportin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

    别名

    Exportin 2

    背景

    Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.

    UniProt

    P55060

    途径

    Protein targeting to Nucleus
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