SERPINA7 抗体 (AA 55-389)
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Quick Overview for SERPINA7 抗体 (AA 55-389) (ABIN7875690)
抗原
See all SERPINA7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 55-389
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原理
- Thyroxine Binding Globulin Antibody / TBG / SERPINA7
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R55-R389) was used as the immunogen for the Thyroxine Binding Globulin antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Thyroxine Binding Globulin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Thyroxine Binding Globulin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SERPINA7 (Serpin Family A Member 7 (SERPINA7))
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别名
- Thyroxine Binding Globulin
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背景
- Thyroxine-binding globulin (TBG) is a globulin protein that in humans is encoded by the SERPINA7 gene. There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
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UniProt
- P05543
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途径
- Hormone Transport
抗原
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