GUCY2D 抗体 (AA 540-570)
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Quick Overview for GUCY2D 抗体 (AA 540-570) (ABIN7875663)
抗原
See all GUCY2D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 540-570
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原理
- Retinal guanylyl cyclase 1 Antibody / GUCY2D
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 540-570 from the human protein was used as the immunogen for the Retinal guanylyl cyclase 1 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Retinal guanylyl cyclase 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Retinal guanylyl cyclase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))
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别名
- Retinal guanylyl cyclase 1
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背景
- This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq].
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UniProt
- Q02846
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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