RNF216 抗体 (AA 538-813)
Our Local Distributor
北京 101111
Quick Overview for RNF216 抗体 (AA 538-813) (ABIN7875630)
抗原
See all RNF216 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 538-813
-
原理
- RNF216 Antibody / TRIAD3
-
纯化方法
- Antigen affinity purified
-
免疫原
- E. coli-derived recombinant human protein (amino acids K538-R813) was used as the immunogen for the RNF216 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the RNF216 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the RNF216 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- RNF216 (Ring Finger Protein 216 (RNF216))
-
别名
- RNF216
-
背景
- E3 ubiquitin-protein ligase RNF216 is an enzyme that in humans is encoded by the RNF216 gene. This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.
-
UniProt
- Q9NWF9
抗原
-