Thrombomodulin 抗体 (AA 537-571)
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Quick Overview for Thrombomodulin 抗体 (AA 537-571) (ABIN7875612)
抗原
See all Thrombomodulin (THBD) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 537-571
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原理
- Thrombomodulin Antibody (C-Terminal Region)
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 537-571 from human THBD was used as the immunogen for the Thrombomodulin antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Thrombomodulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Thrombomodulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Thrombomodulin (THBD)
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别名
- Thrombomodulin
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背景
- Thrombomodulin/THBD/TM/CD141 is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [UniProt]
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UniProt
- P07204
抗原
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