BCL6 抗体 (AA 528-601)
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Quick Overview for BCL6 抗体 (AA 528-601) (ABIN7875587)
抗原
See all BCL6 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 528-601
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原理
- BCL6 Antibody / B-Cell Lymphoma 6 Protein (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 528-601) from the human protein was used as the immunogen for the BCL6 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the BCL6 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the BCL6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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别名
- BCL6
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背景
- Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
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UniProt
- P41182
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途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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