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COMT 抗体 (AA 52-271)

The 小鼠 单克隆 anti-COMT antibody is suitable to detect COMT in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IF, IHC (p) 和 FACS.
产品编号 ABIN7875555
发货至: 中国
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Quick Overview for COMT 抗体 (AA 52-271) (ABIN7875555)

抗原

See all COMT 抗体
COMT (Catechol-O-Methyltransferase (COMT))

适用

  • 69
  • 51
  • 50
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 79
  • 11
  • 3
小鼠

克隆类型

  • 64
  • 29
单克隆

标记

  • 52
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This COMT antibody is un-conjugated

应用范围

  • 57
  • 36
  • 23
  • 16
  • 13
  • 13
  • 13
  • 8
  • 8
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

15C10
  • 抗原表位

    • 15
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 52-271

    原理

    COMT Antibody

    纯化方法

    Affinity purified

    免疫原

    A human recombinant protein (amino acids G52-P271) was used as the immunogen for the COMT antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the COMT antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the COMT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    COMT (Catechol-O-Methyltransferase (COMT))

    别名

    COMT

    背景

    Catechol O-methyltransferase, also called COMT, is one of the major mammalian enzymes involved in the metabolic degradation of catecholamines. This gene is mapped to 22q11.21. Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini.

    UniProt

    P21964

    途径

    Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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