ERN2 抗体 (AA 517-919)
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Quick Overview for ERN2 抗体 (AA 517-919) (ABIN7875536)
抗原
See all ERN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 517-919
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原理
- IRE2 Antibody / ERN2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids K517-P919) was used as the immunogen for the IRE2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the IRE2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the IRE2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
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别名
- IRE2
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背景
- IRE2/ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of IRE2/ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
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UniProt
- Q76MJ5
抗原
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