Glutaminase 抗体 (AA 516-545)
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Quick Overview for Glutaminase 抗体 (AA 516-545) (ABIN7875535)
抗原
See all Glutaminase (GLS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 516-545
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原理
- Glutaminase Antibody / GLS
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 516-545 from the human protein were used as the immunogen for the Glutaminase antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Glutaminase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Glutaminase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Glutaminase (GLS)
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别名
- Glutaminase
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背景
- Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.
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UniProt
- O94925
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途径
- Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effect
抗原
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