PLA2G1B 抗体 (AA 513-541)
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Quick Overview for PLA2G1B 抗体 (AA 513-541) (ABIN7875533)
抗原
See all PLA2G1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 513-541
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原理
- Phospholipase A2 Antibody / PLA2G4A / cPLA2
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 513-541 from the human protein was used as the immunogen for the Phospholipase A2 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Phospholipase A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Phospholipase A2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))
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别名
- Phospholipase A2
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背景
- PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
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UniProt
- P47712
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途径
- Inositol Metabolic Process, VEGF Signaling
抗原
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