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Glypican 3 抗体 (AA 511-580) (CF®555)

The CF®555-conjugated 小鼠 单克隆 anti-Glypican 3 antibody (Clone SPM595) (ABIN7875532) specifically detects Glypican 3 in FACS 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7875532
发货至: 中国
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Quick Overview for Glypican 3 抗体 (AA 511-580) (CF®555) (ABIN7875532)

抗原

See all Glypican 3 (GPC3) 抗体
Glypican 3 (GPC3)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Glypican 3 antibody is conjugated to CF®555

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

SPM595
  • 抗原表位

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    AA 511-580

    原理

    Glypican 3 Antibody

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant fragment containing amino acids 511-580 from the human protein was used as the immunogen for the Glypican-3 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Glypican 3 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the Glypican 3 antibody at 2-8oC, protected from light.
  • 抗原

    Glypican 3 (GPC3)

    别名

    Glypican 3

    背景

    Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100 % in follicular carcinoma and 70 % in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.

    UniProt

    P51654

    途径

    Glycosaminoglycan Metabolic Process
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