Glypican 3 抗体 (AA 511-580) (CF®555)
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Quick Overview for Glypican 3 抗体 (AA 511-580) (CF®555) (ABIN7875532)
抗原
See all Glypican 3 (GPC3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 511-580
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原理
- Glypican 3 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant fragment containing amino acids 511-580 from the human protein was used as the immunogen for the Glypican-3 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the Glypican 3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the Glypican 3 antibody at 2-8oC, protected from light.
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- Glypican 3 (GPC3)
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别名
- Glypican 3
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背景
- Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100 % in follicular carcinoma and 70 % in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.
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UniProt
- P51654
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途径
- Glycosaminoglycan Metabolic Process
抗原
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