Netrin 3 抗体 (AA 51-473)
This 兔 多克隆 antibody specifically detects Netrin 3 in WB, ELISA, IHC (p) 和 IF. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN7875521
发货至:
中国
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Contact Info
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北京 101111
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Quick Overview for Netrin 3 抗体 (AA 51-473) (ABIN7875521)
抗原
See all Netrin 3 (Ntn3) 抗体
Netrin 3 (Ntn3)
适用
人, 大鼠
宿主
兔
克隆类型
多克隆
标记
This Netrin 3 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
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抗原表位
- AA 51-473
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原理
- NTN3 Antibody / Netrin 3
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (R51-R473) was used as the immunogen for the NTN3 antibody.
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亚型
- IgG
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anti-Netrin 3 (Ntn3) (AA 445-458), (Secreted) antibody
Ntn3 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the NTN3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NTN3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Netrin 3 (Ntn3)
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别名
- NTN3
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背景
- Netrins are a family of highly conserved proteins responsible for axon guidance and cell movement throughout neural development. Netrins can be divided into secreted netrins (netrin 1,3,4 and 5) and membrane-tethered glycophosphatidylinositol (GPI)-linked netrins (netrin G1 and G2). Secreted netrins carry their function via interaction with several receptors that include the deleted in colorectal (DCC) family, and the uncoordinated-5 (UNC5-A through UNC5-D) family. Netrin-3 was discovered in 1997 using sequence homology searching of netrin-2. Similarly to other netrins, Netrin-3 plays an important role in the development of the nervous system. Netrin-3 structure consist of a laminin-like domain located on the N-terminal, three epidermal growth factors like repeats (EGF), and a C-terminal netrin-like domain (NTR). Mutations in NTN3, the gene encoding netrin-3 was found to be associated with the development of several carcinomas.
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UniProt
- O00634
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途径
- Regulation of Muscle Cell Differentiation
抗原
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