Neuropilin 1 抗体 (AA 504-827)
Our Local Distributor
北京 101111
Quick Overview for Neuropilin 1 抗体 (AA 504-827) (ABIN7875497)
抗原
See all Neuropilin 1 (NRP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 504-827
-
原理
- NRP1 Antibody / Neuropilin 1
-
纯化方法
- Antigen affinity purified
-
免疫原
- Recombinant human protein (amino acids K504-T827) was used as the immunogen for the NRP1 antibody.
-
亚型
- IgG2a
-
-
-
-
应用备注
- Optimal dilution of the NRP1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the NRP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Neuropilin 1 (NRP1)
-
别名
- NRP1
-
背景
- This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
-
UniProt
- O14786
-
途径
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
抗原
-