电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Recombinant beta Amyloid 抗体 (AA 500-700)

The 兔 单克隆 anti-beta Amyloid antibody (Clone APP-9971R) (ABIN7875427) specifically detects beta Amyloid in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7875427
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant beta Amyloid 抗体 (AA 500-700) (ABIN7875427)

抗原

See all beta Amyloid (Abeta) 抗体
beta Amyloid (Abeta) (Amyloid beta (Abeta))

抗体类型

Recombinant Antibody

适用

  • 88
  • 25
  • 17
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 52
  • 33
  • 2
  • 2
  • 2

克隆类型

  • 55
  • 29
  • 3
单克隆

标记

  • 82
  • 5
  • 2
  • 1
  • 1
This beta Amyloid antibody is un-conjugated

应用范围

  • 49
  • 47
  • 44
  • 25
  • 21
  • 15
  • 9
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

APP-9971R
  • 抗原表位

    • 16
    • 11
    • 10
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 500-700

    原理

    Recombinant Amyloid beta Antibody / APP

    纯化方法

    Protein A affinity

    免疫原

    A portion of amino acids 500-700 from human APP protein was used as the immunogen for the recombinant Amyloid beta antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant Amyloid beta antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant Amyloid beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    beta Amyloid (Abeta) (Amyloid beta (Abeta))

    别名

    Amyloid beta

    背景

    Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the beta-Amyloid and Amyloid A4 proteins, which are present in human platelets. Amyloid deposition is associated with type II diabetes, Down syndrome and a variety of neurological disorders, including Alzheimer s disease. The Amyloid precursor protein (APP) undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of APP leads to the formation of the 4 kDa Amyloid beta/A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.

    UniProt

    P05067

    途径

    Inflammasome
You are here: