SUCLA2 抗体 (AA 50-454)
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Quick Overview for SUCLA2 抗体 (AA 50-454) (ABIN7875410)
抗原
See all SUCLA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-454
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原理
- SUCLA2 Antibody / Succinyl-CoA synthetase beta-A chain
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids Q50-H454) was used as the immunogen for the SUCLA2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SUCLA2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SUCLA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))
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别名
- SUCLA2
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背景
- Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial (SUCLA2), also known as ADP-forming succinyl-CoA synthetase (SCS-A), is an enzyme that in humans is encoded by the SUCLA2 gene on chromosome 13. Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
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UniProt
- Q9P2R7
抗原
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