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Recombinant GLN1 抗体 (AA 50-250)

This 兔 单克隆 antibody specifically detects GLN1 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7875383
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant GLN1 抗体 (AA 50-250) (ABIN7875383)

抗原

See all GLN1 抗体
GLN1 (Glutamine Synthetase (GLN1))

抗体类型

Recombinant Antibody

适用

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宿主

  • 70
  • 22
  • 3
  • 1

克隆类型

  • 48
  • 48
单克隆

标记

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This GLN1 antibody is un-conjugated

应用范围

  • 82
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

GLUL-8889R
  • 抗原表位

    • 19
    • 16
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
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    • 1
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    AA 50-250

    原理

    Glutamine Synthetase Antibody / GLUL (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the Glutamine Synthetase antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the Glutamine Synthetase antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Glutamine Synthetase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    GLN1 (Glutamine Synthetase (GLN1))

    别名

    Glutamine Synthetase

    背景

    Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.

    UniProt

    P15104

    途径

    Positive Regulation of Peptide Hormone Secretion
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