GLN1 抗体 (AA 50-250)
Our Local Distributor
北京 101111
Quick Overview for GLN1 抗体 (AA 50-250) (ABIN7875379)
抗原
See all GLN1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- AA 50-250
-
原理
- Glutamine Synthetase Antibody / GLUL (azide and preservative free)
-
纯化方法
- Protein A/G affinity
-
免疫原
- A portion of amino acids 50-250 was used as the immunogen for the Glutamine Synthetase antibody.
-
亚型
- IgG2b, IgG2c, kappa
-
-
-
-
应用备注
- Optimal dilution of the Glutamine Synthetase antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- -20 °C
-
储存方法
- Aliquot the Glutamine Synthetase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- GLN1 (Glutamine Synthetase (GLN1))
-
别名
- Glutamine Synthetase
-
背景
- Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.
-
UniProt
- P15104
-
途径
- Positive Regulation of Peptide Hormone Secretion
抗原
-