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CD207 抗体 (AA 50-250)

This 小鼠 单克隆 antibody specifically detects CD207 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7875359
发货至: 中国
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北京 101111
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Quick Overview for CD207 抗体 (AA 50-250) (ABIN7875359)

抗原

See all CD207 抗体
CD207 (CD207 Molecule, Langerin (CD207))

适用

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宿主

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小鼠

克隆类型

  • 100
  • 54
单克隆

标记

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This CD207 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

LGRN-7430
  • 抗原表位

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    AA 50-250

    原理

    Langerin Antibody / CD207

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the Langerin antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Langerin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Langerin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD207 (CD207 Molecule, Langerin (CD207))

    别名

    Langerin

    背景

    Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

    UniProt

    Q9UJ71
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